As 19. . 2017. 6. (see CONTRAINDICATIONS) Ophthalmologic Patients who are pregnant or are taking COCs, may experience corneal edema that may cause visual disturbances and changes in tolerance to contact lenses, especially of the rigid type. .

As one of the strongest antagonist of estrogen, levonorgestrel has also been discussed to affect the oxidation of low-density lipoprotein (LDL) cholesterol impacting the endothelium of the cardiac vasculature (Zhu, Bonet, &. Contraindicated in active thrombophlebitis or thromboembolic disorders, undiagnosed abnormal genital bleeding, acute liver disease, benign or malignant liver tumors, known or suspected carcinoma of the breast, history of idiopathic intracranial hypertension, hypersensitivity to levonorgestrel or any of the components of the implants. All prescription and over-the-counter (OTC) drugs in the U. Intrauterine devices (IUDs) are safe and effective and may be used in women on.

. 2022. .

S. . The copper IUD may cause heavier and longer periods, but this should get better after a few months. Past or current cerebrovascular or coronary artery disease; d. 2.